Polynucleotides (PN) are next-generation biostimulatory injectables derived from highly purified DNA fragments — most commonly from salmon or trout sperm — that work by repairing and regenerating skin at a cellular level. Unlike dermal fillers which add volume, Polynucleotides work from within, stimulating the skin’s own fibroblasts to produce new collagen, elastin and hyaluronic acid naturally.
The result is a genuine improvement in skin quality — reduced fine lines, improved hydration, better elasticity and a refreshed, more youthful appearance — with effects that continue to develop over several weeks following treatment.
At Skin Rejuvenation Clinic we offer Polynucleotide treatment for both the delicate eye area and the face, with pricing that varies by brand. Your practitioner will recommend the most appropriate product for your individual concerns.
The eye area is one of the first places to show signs of ageing — fine lines, crepey skin, dark circles and loss of firmness are all common concerns. Polynucleotide injections for the eyes work by regenerating the delicate skin around the orbital area, improving skin quality, reducing fine lines and brightening the appearance of dark hollows — without adding volume or altering the natural contour.
This is a highly specialist treatment requiring precise technique in one of the most delicate areas of the face. Your safety and comfort is our absolute priority throughout.
Pricing varies by brand used — confirmed at consultation.
| Eyes | from £150 |
Polynucleotide facial treatment addresses fine lines, skin laxity, uneven texture and loss of radiance across the face. By stimulating deep tissue repair and new collagen synthesis, the treatment delivers a progressive improvement in overall skin quality that looks completely natural — your skin, restored.
A course of treatments spaced 3–4 weeks apart is typically recommended for optimal results, with maintenance sessions every 6–12 months thereafter.
Pricing varies by brand used — confirmed at consultation.
| Face | from £250 |
💰 10% Off — Book a Course of 3
For best results, Polynucleotides work in a series. Book 3 sessions upfront and receive 10% off — a simple way to commit to your skin and save.
| Procedure Time | 30–45 minutes |
| Back To Work | Same day or next day |
| Anaesthetic | Topical numbing cream available |
| Full Recovery | 2–3 days |
| Sensitivity Period | 24–48 hours |
| Number of Treatments | 3 sessions recommended (3–4 weeks apart) |
| Results Visible | 4–6 weeks after first treatment |
| Duration of Results | 6–12 months |
| Side Effects | Mild redness, swelling and bruising (temporary) |
1. What are Polynucleotides?
Polynucleotides are highly purified DNA fragments that stimulate skin repair and regeneration at a cellular level. They are a biostimulatory injectable — meaning they trigger your skin’s own natural repair processes rather than adding volume.
2. Are they the same as dermal fillers?
No. Dermal fillers add volume to specific areas. Polynucleotides work by regenerating and repairing skin tissue from within — they improve skin quality, texture and elasticity rather than altering structure or shape.
3. Is the treatment painful?
Discomfort is minimal. A topical numbing cream can be applied prior to treatment. Most clients find the procedure very comfortable, particularly for the face. The eye area requires extra care but is well-tolerated.
4. How soon will I see results?
Polynucleotides work progressively. Initial hydration improvements may be noticed within the first week, but the main regenerative effects develop over 4–6 weeks as collagen production increases.
5. How many treatments do I need?
A course of 3 treatments spaced 3–4 weeks apart is recommended for optimal results. Maintenance treatments every 6–12 months help sustain the improvement.
6. Why does pricing vary?
Different Polynucleotide brands (such as Lumieyes, PDRN, Rejuran and others) use different concentrations and formulations. Your practitioner will recommend the most appropriate product for your concerns and confirm exact pricing at consultation.
PRICES FOR POLYNUCLEOTIDES
Slough Clinic
Cippenham London
SL1 5ED
CONTACT US
SKIN REJUVENATION CLINIC
Contact Us: 07376 052 707 – 0800 0831 507
Email: info@skinrejuvenationclinic.london
Harley Street Clinic
London
W1G 9PL
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